New depsidones and isoindolinones from the mangrove endophytic fungus Meyerozyma guilliermondii (HZ-Y₂) isolated from the South China Sea

• Senhua Chen,
• Zhaoming Liu,
• Yayue Liu,
• Yongjun Lu,
• Lei He and
• Zhigang She

Beilstein J. Org. Chem. 2015, 11, 1187–1193, doi:10.3762/bjoc.11.133

• A and B (7 and 9), along with five known compounds were isolated from an endophytic fungus Meyerozyma guilliermondii, derived from the mangrove plant Kandelia obovata. Their structures were elucidated by 1D and 2D NMR spectroscopy and high resolution mass spectrometry (HREIMS). Compounds 1–6

• ; Meyerozyma guilliermondii; Introduction Depsidones are characterized by the presence of cyclic diaryl ethers with an ester link joining the two aromatic rings [1][2]. They have been isolated mainly from various lichens [3][4][5] and other fungi [6][7][8][9][10][11]. These metabolites displayed a wide range

• [13][14][15][16][17]. Recently, a chemical investigation of the endophytic fungal strain Meyerozyma guilliermondii (HZ-Y2), obtained from the roots of the mangrove plant Kandelia obovata, was carried out. The EtOAc extract of a fermentation broth of the fungus showed α-glucosidase inhibitory activity